The is contraindicated during pregnancy and lactation. Women of childbearing age should use reliable and adequate means of contraception.
Since cholesterol and cholesterol biosynthesis products are of great importance for the development of the fetus, the potential risk of inhibition reductase inhibitors outweigh the benefits of its use during pregnancy.
In the case of diagnosing pregnancy reception testosterone enanthate 250 immediately stop.
The data on the allocation of rosuvastatin with breast milk are not available. The appointment of the drug Suvardio ® during lactation is necessary to resolve the issue of termination of breastfeeding.
Dosing and Administration
Inside. At any time, regardless of the meal. The tablet does not chew, do not grind, swallowed whole with water.
Before starting therapy patient must begin to comply with a standard hypocholesterolemic diet and continue to observe her during the entire treatment period.
Dose testosterone enanthate 250® picked individually, taking into account the targets concentrations of cholesterol and individual therapeutic response to treatment. The recommended starting dose per day for patients not previously treated with statins, and patients transferred to the reception of this drug after treatment with other inhibitors reductase. when selecting the starting dose should be guided by kontsentartsiey cholesterol and a possible risk of cardiovascular events in this patient, and should assess the potential risk of side effects. if necessary, after 4 weeks, you can adjust the dose of the drug. In connection with the possible development of adverse effects when taking doses 40 mg compared with lower doses of the drug, the final titration to a maximum dose of 40 mg should be performed, in which when the dose received only in patients with severe hypercholesterolemia and high risk of cardiovascular disease (particularly in patients with familial hypercholesterolemia) 20 mg of cholesterol target concentration has been achieved, and who will be under medical supervision. In appointing the 40 mg dose recommended careful medical supervision. It is not recommended the appointment of a 40 mg dose in patients not previously go to the doctor. Elderly patients For patients older than 65 years, the recommended starting dose of the . In other cases, a dose adjustment based on age is not required.
Patients with renal insufficiency In patients with renal insufficiency, mild or moderate correction doses testosterone enanthate 250 is not required. The recommended starting dose is 5 mg in patients with moderate renal impairment (creatinine clearance less than 60 mL / min). Application at any dose is contraindicated in patients with severe renal insufficiency (creatinine clearance less than 30 ml / min) (see. Section “Contraindications”). Patients with renal moderate insufficiency is contraindicated use of the drug at a dose of 40 mg (see. Section “Contraindications »). patients with hepatic impairment Increased systemic concentrations of rosuvastatin in patients with a score on the scale of Child-Pugh equal to 7 and below, have been identified. However, the increase in systemic concentrations of rosuvastatin were observed in patients with scores . In these patients, liver function should be monitored on a background of rosuvastatin therapy. Data on patients receiving rosuvastatin with a score on the scale of Child-Pugh above 9 no. Patients with liver disease in the active phase of rosuvastatin is contraindicated (see. Section “Contraindications”).Special populations Ethnic groups In patients Mongoloid race may increase systemic rosuvastatin plasma concentrations. The recommended initial d in the Mongoloid race patients is 5 mg. Use of the drug at a dose of 40 mg in these patients is contraindicated (see. Section “Contraindications”). steroiden kaufen
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