In applying the drug in patients with diabetes mellitus, as well as a low-calorie diet should take into account that part of the suspension include sucrose .
in the case should testosterone enanthate be taken as soon as possible to skip the dose missed dose and the next – with an interval of 24 hours.
It is necessary to observe a break 2 hours, while the use of antacids.
The drug should be used with caution in patients with moderate hepatic impairment because of the possibility of development of fulminant hepatitis and severe liver disease.
It has been reported the occurrence of rare serious allergic reactions, such as angioedema edema and anaphylaxis (rarely fatal), as in the case with erythromycin and other macrolides. Some of these reactions to azithromycin become a cause of recurrent symptoms and require long-term observation and treatment.
If you have liver dysfunction symptoms such as rapidly increasing fatigue, jaundice, dark urine, bleeding tendency, hepatic encephalopathy, treatment drug should be discontinued and to carry out research the functional state of the liver.
at moderate renal impairment (creatinine clearance 40 mL / min) therapy with should be performed with caution under the control of renal function.
As with other antibacterial drugs, with drug therapy should regularly examine patients for the presence of non-susceptible organisms and signs development of superinfection, including fungi.
The drug should not be used longer course than indicated in the instructions, as the pharmacokinetic properties of azithromycin allow us to recommend a short and convenient dosing schedule.
It was reported to strengthen the symptoms of myasthenia gravis and cases myasthenic syndrome development in patients receiving treatment azithromycin. No data on the possible interaction between azithromycin and derivatives ergotamine and dihydroergotamine, but due testosterone enanthate to the development of ergotism, while the use of macrolides with derivatives ergotamine and dihydroergotamine, this combination is contraindicated.
Chronic administration of the drug may develop pseudomembranous colitis caused by Clostridium difficile, both in the form of mild diarrhea and severe colitis. With the development of diarrhea in patients receiving azithromycin and for 2 months after completion of therapy should be excluded clostridial pseudomembranous colitis. Drugs inhibiting peristalsis are contraindicated.
After discontinuation of treatment hypersensitivity reactions in some patients may persist, which requires specific therapy under medical supervision.
Azithromycin should be used with caution in patients with impaired liver function and mild to moderate in severity; in patients with impaired renal function, mild to moderate severity.
Effects on ability to drive vehicles, machinery
During treatment caution should be exercised when driving and occupations potentially hazardous activities that require increased attention and psychomotor speed reactions.
Primary packaging for 100 mg / 5 mL:
16.5 g (20 ml suspension) of the drug testosterone enanthate powder in vials with screw caps , unscrewable when pressed with an annular first opening indication . Initial packaging for 200 mg / 5 ml: for 12.4 g (15 ml suspension) 16.5 g (20 ml suspension) 18.6 g (22.5 ml volume of suspension) 24.8 g (slurry 30 ml) and 31.0 g (suspension volume of 37.5 mL) of the drug into the bottles with screw cap, unscrew when pressed with a circular indicator of first opening (PE). Secondary packaging: On 1 bottle with instruction on use, and embedded in a plastic bag measuring syringe cap for the syringe (polyethylene) and a plug with a hole for attachment of a syringe into a cardboard pack.